Trustworthy Weakly Supervised Breast Cancer Detection in Ultrasound Imaging
Abstract: Breast cancer has continued to be a significant health issue in recent years, being the most frequently diagnosed cancer among women in the United States. Early-stage breast cancer lacks apparent symptoms in the early stage of breast cancer; thus, many patients miss the best chance to cure it. Breast Ultrasound (BUS) imaging has emerged as a crucial diagnostic tool. Yet, the inherent challenges in BUS imaging, such as low contrast and noise, impede accurate breast cancer diagnosis by doctors. Computer-aided-diagnosis (CAD) systems are proposed to help radiologists interpret BUS images, make a more precise diagnosis, and reduce their workload. Breast cancer detection plays a crucial role in the CAD system. Training a fully supervised model for detecting breast cancer necessitates many manual annotations. Several weakly supervised frameworks for object detection have been developed to minimize the requirement for extensive annotations. During the SpF 2023 award period, the research team developed two such frameworks for natural images and breast cancer detection. However, trustworthiness is the most critical aspect of smart health applications. Constructing a trustworthy deep-learning model requires extensive datasets. Additionally, previous methods do not offer a qualitative assessment of the models’ trustworthiness. To overcome these hurdles, the researchers propose a new, trustworthy, weakly supervised framework for breast cancer detection named BUSwiNet. This framework utilizes only image-level labels (cancer/non cancer). It is capable of identifying the bounding boxes of breast tumors in breast ultrasound (BUS) images, as well as determining whether the tumor is cancerous. Moreover, the research aims to develop a method using Bayesian Neural Networks to evaluate the trustworthiness of breast cancer detection models quantitatively.